Basically when it comes to pipe tuning your looking at torque curve. This can be adjusted with any pipe that offers multiple exhaust tip sizes.
4stroke bikes are very similar to auto engines in theory. The bigger the opening the faster the engine will rev. The faster you get the exhaust out the faster you can get the next intake stroke in. So your end cap opening will determine how you turn on the torque curve. Smaller opening slower curve.
4Stroke usually have plenty of top end. You want a snappy bottom end hit espescially for those Oh crapp situations. Unless you run in the desert top end is not much of an issue.
You can also adjust your hit playing with gearing. For example if you have a 14 tooth front sproket and you go to a 15 you will gain more on top and less on the bottom. A 13 tooth will give you more on the bottom and less on the top.
You first must determine what kind of riding you will be doing most of. If it is trails or track type riding you don't really need top end because you probably will never get to see those rpm ranges being as soon as your on the gas your back off of it.
How often are you really going to be topping out 5th gear. On a 450 not very much. If your hitting 5th then you are going over 70 mph. Where do you need that?
I would start off like rpyfz450 stated and take out the tip on the stock exhaust. That will give you a lot of punch to start with. An after market pipe won't give you too much more than that, but they look and sound cool.